WASAbis 30capsules
$180.00
-
PT
WASAbis(R)
A product that is made with only domestically produced true wasabi and contains the scarce health-promoting componet,6-MSITC.
6-MSITC (6-Methylsulfinylhexyl Isothiocyanate) refers to the main health component contained in small quantities in the rhizome of wasabi after removing wasabi's unique pungent components.
It is a nutritional ingredient that can improve cognitive functions, such as decision-making abilities (the ability to accurately process information) and attentiveness.
It can also limit the production of active enzymes with its powerful antibacterial properties.
The “decision-making ability*1/attentiveness,”
which are parts of the cognitive functions of middle and older-aged persons with no exercise habits, have improved.
Results of animal studies have reported on the effects of 6-MSITC on cognitive functions. *2,3 As exercise routines improve brain functions *4, 5, 37 healthy middle and older age males and females (Placebo group: 18, Wasabi-derived 6-MSITC Group: 19) with no routine exercise habits and with self-awareness of forgetfulness were given wasabi-derived 6-MSITC to investigate the effects on the brain functions.
As a result, as displayed in the diagram to the left, the variations in the eighth-week indicated that the wasabi-derived 6-MSITC group showed improvements compared to the placebo group*6, and some cognitive functions such as decision-making ability (ability to accurately process information) and attentiveness showed improvements. *8
The evaluation of attention forms a central part of cognitive functional evaluation. Attention is not a single function, but rather is connected to various cognitive functions and plays a key role in supporting learning, memory and executive functions, and the activity of working memory.
Cellular tests report that 6-MSITC has “antioxidant effects” *9 by inhibiting the production of active enzymes and also has “platelet aggregation inhibiting effects.” *10 It is possible that these effects limit the damages on the cells, thereby contributing to improved cognitive functions.
*1
Ability to correctly process information
*2
Protective Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate on A 1-42-Induced Cognitive Deficit, Oxidative Stress, Inflammation, and Apoptosis in Mice. Int. J. Mol. Sci. 19,2083-2102(2018)
*3
Neuroprotection by 6-(methylsulfinyl)hexyl isothiocyanate in a 6-hydroxydopamine mouse model of Parkinson’s disease. Brain Reserch: 1589,93-104(2014)
*4
Correlation between cognitive functions and exercise/physical activity in the elderly, 25th Health and Medical Science Research Grant Papers, 129-136 (2010)
*5
Acute moderate exercise elicits increased dorsolateral prefrontalactivation and improves cognitive performance with Stroop test. Neuroimage, 50, 1702-1710(2010)
*6
A placebo is a drug that contains no active ingredient (has no medicinal effect). It looks like a real drug, but does not contain any medicinal ingredients. It is a fake drug.
*7
p < 0.05 (2 samples, t-test)
*8
The effects of wasabi root extract rich in 6-(methylsulfinyl)hexyl isothiocyanateon neurocognitive functions in cognitively intact middle-aged and older adults: a randomized, double-blind, placebo-controlled trial. Jpn Pharmacol Ther. 47, 275-286 (2019). Report for systematic review
*9
Inhibitory Effects of 6-Methylsulfinylhexyl Isothiocyanate on Superoxide Anion Generation from Differentiated HL-60 Human Promyelocytic Leukemia Cells. Food Science and Technology Research, 23, 343-348(2017)
*10
All About Wasabi, Japan Scientific Societies Press (2006)
A product that is made with only domestically produced true wasabi and contains the scarce health-promoting componet,6-MSITC.
6-MSITC (6-Methylsulfinylhexyl Isothiocyanate) refers to the main health component contained in small quantities in the rhizome of wasabi after removing wasabi's unique pungent components.
It is a nutritional ingredient that can improve cognitive functions, such as decision-making abilities (the ability to accurately process information) and attentiveness.
It can also limit the production of active enzymes with its powerful antibacterial properties.
The “decision-making ability*1/attentiveness,”
which are parts of the cognitive functions of middle and older-aged persons with no exercise habits, have improved.
Results of animal studies have reported on the effects of 6-MSITC on cognitive functions. *2,3 As exercise routines improve brain functions *4, 5, 37 healthy middle and older age males and females (Placebo group: 18, Wasabi-derived 6-MSITC Group: 19) with no routine exercise habits and with self-awareness of forgetfulness were given wasabi-derived 6-MSITC to investigate the effects on the brain functions.
As a result, as displayed in the diagram to the left, the variations in the eighth-week indicated that the wasabi-derived 6-MSITC group showed improvements compared to the placebo group*6, and some cognitive functions such as decision-making ability (ability to accurately process information) and attentiveness showed improvements. *8
The evaluation of attention forms a central part of cognitive functional evaluation. Attention is not a single function, but rather is connected to various cognitive functions and plays a key role in supporting learning, memory and executive functions, and the activity of working memory.
Cellular tests report that 6-MSITC has “antioxidant effects” *9 by inhibiting the production of active enzymes and also has “platelet aggregation inhibiting effects.” *10 It is possible that these effects limit the damages on the cells, thereby contributing to improved cognitive functions.
*1
Ability to correctly process information
*2
Protective Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate on A 1-42-Induced Cognitive Deficit, Oxidative Stress, Inflammation, and Apoptosis in Mice. Int. J. Mol. Sci. 19,2083-2102(2018)
*3
Neuroprotection by 6-(methylsulfinyl)hexyl isothiocyanate in a 6-hydroxydopamine mouse model of Parkinson’s disease. Brain Reserch: 1589,93-104(2014)
*4
Correlation between cognitive functions and exercise/physical activity in the elderly, 25th Health and Medical Science Research Grant Papers, 129-136 (2010)
*5
Acute moderate exercise elicits increased dorsolateral prefrontalactivation and improves cognitive performance with Stroop test. Neuroimage, 50, 1702-1710(2010)
*6
A placebo is a drug that contains no active ingredient (has no medicinal effect). It looks like a real drug, but does not contain any medicinal ingredients. It is a fake drug.
*7
p < 0.05 (2 samples, t-test)
*8
The effects of wasabi root extract rich in 6-(methylsulfinyl)hexyl isothiocyanateon neurocognitive functions in cognitively intact middle-aged and older adults: a randomized, double-blind, placebo-controlled trial. Jpn Pharmacol Ther. 47, 275-286 (2019). Report for systematic review
*9
Inhibitory Effects of 6-Methylsulfinylhexyl Isothiocyanate on Superoxide Anion Generation from Differentiated HL-60 Human Promyelocytic Leukemia Cells. Food Science and Technology Research, 23, 343-348(2017)
*10
All About Wasabi, Japan Scientific Societies Press (2006)